Pyrroloquinoline Quinone Alleviates Oxidative Damage Induced by High Glucose in HepG2 Cells
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چکیده
منابع مشابه
Nanoceria Attenuated High Glucose-Induced Oxidative Damage in HepG2 Cells
OBJECTIVE Hyperglycemia, a common metabolic disorder in diabetes, can lead to oxidative damage. The use of antioxidants can benefit the control and prevention of diabetes side effects. This study aims to evaluate the effect of nanoceria particles, as an antioxidant, on glucose induced cytotoxicity, reactive oxygen species (ROS), lipid peroxidation (LPO) and glutathione (GSH) content in a human ...
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The Entner-Doudoroff pathway was shown to be induced for oxidative glucose metabolism when Escherichia coli was provided with the periplasmic glucose dehydrogenase cofactor pyrroloquinoline quinone (PQQ). Induction of the Entner-Doudoroff pathway by glucose plus PQQ was established both genetically and biochemically and was shown to occur in glucose transport mutants, as well as in wild-type E....
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Background: Clinical evidence indicates the diabetes-induced impairment of osteogenesis caused by a decrease in osteoblast activity. Flavonoids can increase the differentiation and mineralization of osteoblasts in a high-glucose state. However, some flavonoids such as luteolin may have the potential to induce cytotoxicity in osteoblast-like cells. This study was performed to investigate whether...
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ژورنال
عنوان ژورنال: Saudi Journal of Biological Sciences
سال: 2021
ISSN: 1319-562X
DOI: 10.1016/j.sjbs.2021.06.063